PUBLICATIONS |
peer-reviewed publications
Riccardo Pianezza, Almorò Scarpa, Anna Haider, Sarah Signor*, Robert Kofler*. Spatio-temporal tracking of three novel transposable element invasions in Drosophila melanogaster over the last 30 years. *co-last Molecular Biology and Evolution, 2025 msaf143
Scarpa, Almorò, Riccardo Pianezza, Hannah R. Gellert, Anna Haider, Bernard Y. Kim, Eric C. Lai, Robert Kofler*, and Sarah Signor*. Double trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years. *co-last, Nature Communications , 2025, 16(1): 516.
Ramirez-Lanzas, Claudia, Marlies Dolezal, Sarah Signor, Christian Schlötterer, Neda Barghi. Tracking polygenic adaptation: phenotypic stasis after rapid adaptation in large populations of Drosophila, 2025, bioRxiv doi: https://doi.org/10.1101/2025.06.09.658643
Pritam, Shashank, Almorò Scarpa, Robert Kofler, and Sarah Signor. The impact of insertion bias into piRNA clusters on the invasion of transposable elements. bioRxiv, 2024.
Pritam, Shashank, and Sarah Signor. Evolution of piRNA-guided defense against transposable elements. Trends in Genetics, 2024.
Pianezza, R., Scarpo, A., Narayanan, P., Signor, S*., Kofler, R*. Spoink, a LTR retrotransposon, invaded Drosophila melanogaster populations in the 1990s. *co-last PLoS Genetics, 2024, 20(3), p.e1011201.
Nanni, A., Titus-MxQuillan, J., Bankole, K. S., Pardo-Palacios, F., Signor, S., Vlaho, S., Moskalenko, O., Morse, A., Rogers, R. L., Conesa, A., McIntyre L. M. Nucleotide-level distance metrics to quantify alternative splicing implemented in TranD. Nucleic Acids Research, 2024, gkae056, https://doi.org/10.1093/nar/gkae056
Boateng-Sarfo, G., Scherping Bustos, F., Mammadov, M., Signor, S. Evolution of plasticity in response to ethanol between recently separated populations of D. melanogaster with different ecological histories. 2023. bioRxiv. https://doi.org/10.1101/2023.06.22.546145.
Signor, S., Vedanayagam J., Kim, Bernard Y., Wierzbicki, F., Kofler, R., and Eric C. Lai. 2023. Rapid evolutionary diversification of the flamenco locus across simulans clade Drosophila species. PLoS Genetics, 19(8): e1010914.
Adalena V Nanni, Natalie Martinez, Rita Graze, Alison Morse, Jeremy R B Newman, Vaibhav Jain, Srna Vlaho, Sarah Signor, Sergey V Nuzhdin, Rolf Renne, Lauren M McIntyre. 2023. Sex-Biased Expression Is Associated With Chromatin State in Drosophila melanogaster and Drosophila simulans, Molecular Biology and Evolution, 40(5): msad078, https://doi.org/10.1093/molbev/msad078
Wierzbicki, F. Kofler, R., and Signor, S. 2023. Evolutionary dynamics of piRNA clusters in Drosophila. Molecular Ecology. 32(6):1306-1322.
Signor, S., Yocum, G., and Bowsher J. 2022. Life stage and the environment as effectors of transposable element activity in Megachile rotundata and Osmia lignaria. Journal of Insect Physiology, 137:104361.
Tiedeman, Z. and Signor, S. 2020. The transposable elements of the Drosophila serrata reference panel. Genome Biology and Evolution, evab100.
Signor, S. 2020. Evolution of phenotypic plasticity in response to ethanol between sister species with different ecological histories (Drosophila melanogaster and D. simulans). American Naturalist. 196(5). 620-633.
Signor, S. 2020. Transposable element copy number in individual genotypes of Drosophila simulans. Ecology and Evolution.10(7):3402-3412.
Signor, S., and Nuzhdin, S. 2019. Compensatory evolution of gene expression. Trends in Genetics. 34(12):P890-891.
Signor, S., Nuzhdin, S. 2018. Dynamic changes in gene expression and alternative splicing mediate the response to acute alcohol exposure. Heredity. 121(4):342-360.
Signor, S., Ali, S., Konstantin, K., Nuzhdin, S. 2019. Novel approach to quantitative spatial gene expression uncovers genetic stochasticity in the developing Drosophila eye. Evolution and Development. 21(3):157-171.Signor, S., Nuzhdin, S. 2018.The evolution of gene expression in cis and trans. Trends in Genetics. 34(7): 532-544.
Signor, S., New, F., Nuzhdin, S. 2018. A large panel of Drosophila simulans reveals an abundance of common variants. Genome Biology and Evolution. 10 (1): 189-206
Signor, S., Abbasi, M., Marjoram, P., Nuzhdin, S. 2017. Conservation of social effects (Ψ) between two species of Drosophila despite reversal of sexual dimorphism. Ecology and Evolution. 7(23):10031-10041
Signor, S. 2017. Population genomics of Wolbachia and mtDNA in Drosophila simulans from California. Scientific Reports. 7:13369
Signor, S., Abbasi, M., Marjoram, P., Nuzhdin, S. (2017) Social effects for locomotion vary between environments in Drosophila melanogaster males and females. Evolution. 71(7):1765-1775.
Signor, S., Yang, L., Rebeiz, M., Kopp, A. (2016) Genetic convergence in the evolution of male specific color patterns in Drosophila. Current Biology. 26(18):2423-2433.
Signor, S., Arbeitman, M. Nuzhdin, S. (2016) Gene networks and developmental context: the importance of understanding complex gene expression patterns in evolution. Evolution & Development, 18(3): 201-209.
Signor, S., Ng, C.S., Podlaha, O., Seher, T., Kopp, A. (2013) Genomic resources for multiple species in the Drosophila ananassae species group. Fly. 7(1): 47-57.
Seher, T.D., Ng, C.S., Signor, S., Podhala, O., Barmina, O., Kopp, A. (2012) Genetic basis of a violation of Dollo’s Law: re-evolution of rotating sex combs in Drosophila. Genetics. 194(4):1465-75.
non-peer reviewed publications
Signor, S. A. (2019) Mating Behavior: Structure meets function. eLife.
Riccardo Pianezza, Almorò Scarpa, Anna Haider, Sarah Signor*, Robert Kofler*. Spatio-temporal tracking of three novel transposable element invasions in Drosophila melanogaster over the last 30 years. *co-last Molecular Biology and Evolution, 2025 msaf143
Scarpa, Almorò, Riccardo Pianezza, Hannah R. Gellert, Anna Haider, Bernard Y. Kim, Eric C. Lai, Robert Kofler*, and Sarah Signor*. Double trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years. *co-last, Nature Communications , 2025, 16(1): 516.
Ramirez-Lanzas, Claudia, Marlies Dolezal, Sarah Signor, Christian Schlötterer, Neda Barghi. Tracking polygenic adaptation: phenotypic stasis after rapid adaptation in large populations of Drosophila, 2025, bioRxiv doi: https://doi.org/10.1101/2025.06.09.658643
Pritam, Shashank, Almorò Scarpa, Robert Kofler, and Sarah Signor. The impact of insertion bias into piRNA clusters on the invasion of transposable elements. bioRxiv, 2024.
Pritam, Shashank, and Sarah Signor. Evolution of piRNA-guided defense against transposable elements. Trends in Genetics, 2024.
Pianezza, R., Scarpo, A., Narayanan, P., Signor, S*., Kofler, R*. Spoink, a LTR retrotransposon, invaded Drosophila melanogaster populations in the 1990s. *co-last PLoS Genetics, 2024, 20(3), p.e1011201.
Nanni, A., Titus-MxQuillan, J., Bankole, K. S., Pardo-Palacios, F., Signor, S., Vlaho, S., Moskalenko, O., Morse, A., Rogers, R. L., Conesa, A., McIntyre L. M. Nucleotide-level distance metrics to quantify alternative splicing implemented in TranD. Nucleic Acids Research, 2024, gkae056, https://doi.org/10.1093/nar/gkae056
Boateng-Sarfo, G., Scherping Bustos, F., Mammadov, M., Signor, S. Evolution of plasticity in response to ethanol between recently separated populations of D. melanogaster with different ecological histories. 2023. bioRxiv. https://doi.org/10.1101/2023.06.22.546145.
Signor, S., Vedanayagam J., Kim, Bernard Y., Wierzbicki, F., Kofler, R., and Eric C. Lai. 2023. Rapid evolutionary diversification of the flamenco locus across simulans clade Drosophila species. PLoS Genetics, 19(8): e1010914.
Adalena V Nanni, Natalie Martinez, Rita Graze, Alison Morse, Jeremy R B Newman, Vaibhav Jain, Srna Vlaho, Sarah Signor, Sergey V Nuzhdin, Rolf Renne, Lauren M McIntyre. 2023. Sex-Biased Expression Is Associated With Chromatin State in Drosophila melanogaster and Drosophila simulans, Molecular Biology and Evolution, 40(5): msad078, https://doi.org/10.1093/molbev/msad078
Wierzbicki, F. Kofler, R., and Signor, S. 2023. Evolutionary dynamics of piRNA clusters in Drosophila. Molecular Ecology. 32(6):1306-1322.
Signor, S., Yocum, G., and Bowsher J. 2022. Life stage and the environment as effectors of transposable element activity in Megachile rotundata and Osmia lignaria. Journal of Insect Physiology, 137:104361.
Tiedeman, Z. and Signor, S. 2020. The transposable elements of the Drosophila serrata reference panel. Genome Biology and Evolution, evab100.
Signor, S. 2020. Evolution of phenotypic plasticity in response to ethanol between sister species with different ecological histories (Drosophila melanogaster and D. simulans). American Naturalist. 196(5). 620-633.
Signor, S. 2020. Transposable element copy number in individual genotypes of Drosophila simulans. Ecology and Evolution.10(7):3402-3412.
Signor, S., and Nuzhdin, S. 2019. Compensatory evolution of gene expression. Trends in Genetics. 34(12):P890-891.
Signor, S., Nuzhdin, S. 2018. Dynamic changes in gene expression and alternative splicing mediate the response to acute alcohol exposure. Heredity. 121(4):342-360.
Signor, S., Ali, S., Konstantin, K., Nuzhdin, S. 2019. Novel approach to quantitative spatial gene expression uncovers genetic stochasticity in the developing Drosophila eye. Evolution and Development. 21(3):157-171.Signor, S., Nuzhdin, S. 2018.The evolution of gene expression in cis and trans. Trends in Genetics. 34(7): 532-544.
Signor, S., New, F., Nuzhdin, S. 2018. A large panel of Drosophila simulans reveals an abundance of common variants. Genome Biology and Evolution. 10 (1): 189-206
Signor, S., Abbasi, M., Marjoram, P., Nuzhdin, S. 2017. Conservation of social effects (Ψ) between two species of Drosophila despite reversal of sexual dimorphism. Ecology and Evolution. 7(23):10031-10041
Signor, S. 2017. Population genomics of Wolbachia and mtDNA in Drosophila simulans from California. Scientific Reports. 7:13369
Signor, S., Abbasi, M., Marjoram, P., Nuzhdin, S. (2017) Social effects for locomotion vary between environments in Drosophila melanogaster males and females. Evolution. 71(7):1765-1775.
Signor, S., Yang, L., Rebeiz, M., Kopp, A. (2016) Genetic convergence in the evolution of male specific color patterns in Drosophila. Current Biology. 26(18):2423-2433.
Signor, S., Arbeitman, M. Nuzhdin, S. (2016) Gene networks and developmental context: the importance of understanding complex gene expression patterns in evolution. Evolution & Development, 18(3): 201-209.
Signor, S., Ng, C.S., Podlaha, O., Seher, T., Kopp, A. (2013) Genomic resources for multiple species in the Drosophila ananassae species group. Fly. 7(1): 47-57.
Seher, T.D., Ng, C.S., Signor, S., Podhala, O., Barmina, O., Kopp, A. (2012) Genetic basis of a violation of Dollo’s Law: re-evolution of rotating sex combs in Drosophila. Genetics. 194(4):1465-75.
non-peer reviewed publications
Signor, S. A. (2019) Mating Behavior: Structure meets function. eLife.